mTOR pathway
The mammalian target of rapamycin (mTOR) is a core regulator that enables cells to sense nutrient and energy status and control protein synthesis and autophagy. pass A persistently active mTOR signaling pathway can accelerate aging;
Sirtuins family
This is a class of NAD+-dependent deacetylases, known as "longevity proteins", involved in regulating DNA repair, inflammation Multiple aging-related processes such as metabolism and stress resistance;
FOXO protein family
These are important transcription factors that play a central role in regulating stress resistance, apoptosis, metabolism, and autophagy. They are downstream effectors of the insulin/IGF-1 signaling pathway, and the inhibition of this pathway has been shown to be closely associated with longevity;


